Single Cell Immune Sequencing

Targeted paired chain single cell TCR and BCR sequencing for detailed adaptive immune receptor insights

When RNA is extracted for bulk repertoire sequencing, information related to the cognate pairing of BCR and TCR chains is lost. iRepertoire's iPair is the first consumer-based single-cell immune sequencing service specifically designed for capturing physically paired variable regions in T cells and B cells.

Our customizable service can also provide phenotypic analysis coupled with the single cell VDJ data, providing specific and detailed immune insight of your samples.

Choose iRepertoire’s iPair powerful and flexible technology for your next experiment

Cost-effective Single cell VDJ sequencing
Fully customizable service
Scientific support from expert immunologists
Detailed BCR and TCR repertoire analysis
Includes basic bioinformatic analysis with a user-friendly GUI
Compatible with human or mouse samples
Track VDJ recombination in B or T cells
Full CDR3 analysis
Alpha/beta TCR pairing
Gamma/delta TCR pairing
IgH kappa/lambda pairing
Option to add phenotyping with Immunosight

Supportive software makes analysis simpler. Find the answers in your sequencing data with the iPair Analyzer

Complementary data analysis
Well-by-well GUI lets you filter by read depth, unique CDR3s, chain usage, or V/D/J usage
Parse out significant data points to streamline downstream analysis
Generate heatmaps and T-SNE plots
Easily compare single-chain comparison analysis to bulk sequencing data

Capture paired BCR/TCR chains with single cell immune sequencing

Targeted paired chain single cell TCR and BCR sequencing for detailed adaptive immune receptor insights

Choose iRepertoire’s iPair powerful and flexible technology for your next experiment

Supportive software makes analysis simpler. Find the answers in your sequencing data with the iPair Analyzer

Let us help plan your project. Get a free consultation with one of our experts.

CASE STUDY

Applications for single cell immune sequencing