Targeted Single Cell BCR and TCR Sequencing for Paired Chain Profiling
Explore Single-Cell V(D)J Sequencing for Paired TCR/BCR Chain Insights
When RNA is extracted for bulk repertoire sequencing, information related to the cognate pairing of BCR and TCR chains is lost. iRepertoire's iPair is the first consumer-based single-cell immune sequencing service specifically designed for capturing physically paired variable regions in T cells and B cells.
Our customizable service can also provide phenotypic analysis coupled with the single cell VDJ data, providing specific and detailed immune insight of your samples.
Choose iRepertoire’s iPair powerful and flexible technology for your next experiment
- Cost-effective Single cell VDJ sequencing
- Fully customizable service
- Scientific support from expert immunologists
- Detailed BCR and TCR sequencing analysis
- Includes basic bioinformatic analysis with a user-friendly GUI
- Compatible with human or mouse samples
- Track VDJ recombination in B or T cells
- Full CDR3 analysis
- Alpha/beta TCR pairing
- Gamma/delta TCR pairing
- IgH kappa/lambda pairing
- Option to add phenotyping with Immunosight
Supportive software makes analysis simpler. Find the answers in your sequencing data with the iPair Analyzer
- Complementary data analysis
- Well-by-well GUI lets you filter by read depth, unique CDR3s, chain usage, or V/D/J usage
- Parse out significant data points to streamline downstream analysis
- Generate heatmaps and T-SNE plots
- Easily compare single-chain comparison analysis to bulk sequencing data